B.Pharmacy 6th Semester Question Paper Pdf Download
Semester- 6th-
- Here you'll get B.pharmacy Previous Year Question Paper subject wise.
- These are the pharmcology previous years question Paper Of B.pharmacy provide and help student to realize highest marks in exam.
- This questions paper are of b.pharm 6th sem. as per latest PCI syllabus.
BP- 601T - Medicinal Chemistry III-
Medicinal Chemistry - III
Time : Three Hours
Маximum Маrks: 75
i) Attempt any five questions.
ii) All questions carry equal marks.
1) Write a note on penicillins with example.
Brief about B-lactamase inhibitors.
a) Discuss structure activity relationship of tetracycline.
b) Write a note on amino glycosides.
2) Discuss basic concepts and application of prodrugs design with suitable examples.
a) Write classification of antimalarials giving suitable examples of each class.
b) Give structure activity relationship of quinolines as antimalarial drugs.
3) Discuss various physicochemical parameters used in Quantitative Structure Activity Relationship (QSAR). Brief
about combinatorial chemistry.
4) Write classification and SAR of sulfonamides with structural
representation. Give synthesis of any one drug from sulfonamides category.
a) Write a note on antifungal agents.
b) Give synthesis and applications of metronidazole and diethylcarbamazine citrate.
Write notes on any two of the following:
a) Antiviral agents
b) Synthesis and therapeutic applications of chloramphenicol and isoniozid.
c) Macrolides
BP- 602T- Pharmcology III-
B.Pharmacy VI Semester (PCI Scheme)
Examination, June 2020
Choice Based Grading System (CBGS)
Pharmacology-III
Time : Three Hours
Maximum Marks : 75
Note: i) Attempt any five questions.
किन्हीं पाँच प्रश्नों को हल कीजिए।
ii) All questions carry equal marks.
1. Classify antiasthmatic drugs on the basis of mechanism of action. Describe pathophysiology of Asthma.
2. Discuss the principles of Chemotherapy. Enlist the mode of action of penicillin and aminoglycosides with their respective side effect.
3. Write the pathophysiology of gastric ulcer. Write the pharmacology of Proton Pump inhibitor.
write notes on
a) teratogenic and mutagenicity
b) Treatment and management of urinary tract infection
5. Explain in brief general principles of Poisoning. Give a detailed note on barbiturate poisoning.
6. Give the pharmacological classification of antiviral drugs with mode of action of any one potential antiviral drug.
7. Classity antitubercular drug and discuss first line antitubercular drugs.
8. Write note on (any three)
a) Aminoglycosides
b) Sulfonamide and cotrimoxazole
c) Nasal Decongestants
d) Emetics and antiemetics
BP- 603T- Herbal Drug Technology -
B.pharmacy VI Semester
Examination,
Herbal Drug Technology
Time: Three Hours
Maximum Marks: 75
Note: i) Atempt any five questions.
ii) All questions carry equal marks.
ii) Draw neat and clear diagram where necessary.
1) What are herb and herbal medicines? Explain the processing of herbal raw material in brief.
2) Explain in brief about good agriculture practices in cultivation of medicinal plants.
3) Discuss Indian system of Medicines. Explain in brief about principal involved in Ayurveda and Siddha.
4. What are Nutraceuticals? Elements for diabetes ande cancer in brief.
5). a) Discuss the source and description of herbal origins for used in herbal cosmetic as protective agent and fixed oil.
b) Discuss the source and description of herbal origins for used in herbal cosmetic as sweeteners and binder.
6. a) Discuss about herbal formulation for syrup and mixtures.
b) Write a detail note on WHO and ICH guidelines for the assessment of herbal drugs.
8. Write short note on following:
a) Stability study of herbal drugs.
b) Patent and IPR for natural products
BP- 604T- Biopharmceutics and Biopharmcokinetics-
B.Pharmacy VI Semester
Choice Based Grading System (CBGS)
Biopharmaceuties and Pharmacokineties
Time : Three Hours
Maximum Marks: 75
1. a) Describe various mechanisms of drug absorption.
b) Discuss Physico-chemical properties affecting drug absorption through GIT.
2 a)Discuss Kinetics of protein binding of drug and its significance.
b)Describe factors affecting protein binding of drugs.
3. a) Discuss various routes of excretion of drugs.
b) Discuss the basic pathways of drug metabolism.
4. a) Describe the methods to enhance dissolution rates and bioavailability of drugs.
b) Discuss in-vitro drug dissolution models.
5. a) Describe one compartment open model for determination of K and CI after intravenous bolus administration.
b) Discuss methods for determination of K, for drugs following one compartment open model after extravascular administration.
6. a) What is Non-linear Pharmacokinetics? Explain factors causing Non-linearity.
b) Describe methods for determination of K and Vma Using Michaclis-Meten kinetics.
7. a) Explain steady state drug levels and time required to achieve it with suitable example.
b) Discuss the calculation of loading and maintenance doses.
8. Write short notes on :
a) Absolute and relative bioavailability
b) Non-compartmental models
c) Apparent volume of distribution and its significance
d) Physiological pharmacokinetic models
BP -605T : Pharmceutical Biotechnology-
B.Pharmacy VI Semester
Choice Based Grading System (CBGS)
Pharmaceutical Biotechnology
Time: Three Hours
Maximum Marks: 75
1. a) Describe the term Pharmaceutical Biotechnology? What is the role of biotechnology in the field of pharmaceutical research with suitable examples?
b) Give the definition of immobilization?
C) Describe the different methods of immobilization with suitable example.
2. a) Describe the term biosensor. Write the working and application of biosensors used in Phamaceutical Industry.
b) What is Recombinant DNA technology? Describe the applications of genetic engineering in the pharmaceutical
industry.
3. a)Discuss the role of genetic enginering in the production of Vaccine-Hepatitis-B and Hormone-Insulin.
b) Discuss various PCR techniques used along with their application in the field of biotechnology.
4. a)Write in detail production of monoclonal antibodies by Hybridization Technology.
b) Explain the difference in Blood Products and Plasma Substitutes.
5. a)Discuss in detail the provisions for the storage and stability conditions of official Vaccines.
b)Describe the methods of DNA and mRNA detection.
6. a)What is Mutation? Describe the sources of mutation discussing the different types of mutation in detail.
b) What is fermentation process? Discuss the construction, working and control of a large scale industrial fermentor.
7. a) Give detail note on production of Vitamin B12 and Griseofulvin.
b) Write a detail note on (any two):
i)Penicillinase
ii) Peroxidase
ii) Humoral and Cellular immunity
iv) Transduction and Conjugation
8. a) Discuss in detail the various steps involved in gene cloning technology.
b) Define hypersensitivity and explain the various types of hypersensitivity reactions in detail with suitable examples.
BP -606T : Quality Assurance-
Quality Assurance
Time: Three Hours
Marimum Marks: 75
1. Discuss in detail the concepts of Quality control, quality assurance and GMP
2. a)Discuss the protocol for conduct of a nonclinical laboratory study.
b) What are the tools and elements of QbD program?
3. Write notes on (any two):
a) Good warehousing practices
b) Principles and procedures of NABL accreditation
c) Quality review and quality documentation
4. a) Write a note an NCH stability testing guidelines.
b) Describe the design. construction and plant layout of pharmaceutical industry.
5. Write notes on (any two):
a) Complaints and evaluation of complaints
b)Types, importance and scope of validation
c) Testing facilities operation and disqualification of testing facilities.
6. Explain the quality control tests for containers, rubber closures and secondary packing materials.
7. Write notes on (any two):
a) Purchase specifications and maintenance of stores for raw materials
b) Master formula record
c)Benefits and elements of ISO 9000 and ISO 14000
8. Write notes on (any two):
a)Batch formula records
b) Elemets and philosophies of total quality management
c)General principles of analytical mehod validation
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